Volume 16; Issue suppl 3

Main
Neuro-Oncology
Volume 16; Issue suppl 3

Neuro-Oncology

Volume 16; Issue suppl 3

1

ASSOCIATION OF CD133 EXPRESSION AND IDH MUTATION WITH RECURRENCE PATTERN IN HIGH GRADE GLIOMAS

Sonoda, Y., Shibahara, I., Sonoda, Y., Kawaguchi, T., Saito, R., Kanamori, M., Yamashita, Y., Watanabe, T., Kumabe, T., Watanabe, M., Suzuki, H., Tominaga, T.

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Year:

2014

Language:

english

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english, 2014

2

DETECTION OF CIRCULATING TUMOR DNA IN EARLY AND LATE STAGE HUMAN MALIGNANCIES

Bettegowda, C., Sausen, M., Leary, R., Kinde, I., Agrawal, N., Bartlett, B., Wang, H., Luber, B., Kinzler, K., Vogelstein, B., Papadopoulos, N.

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2014

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english

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3

QUANTIFICATION OF PRONEURAL GENE-EXPRESSION SIGNATURE OF GLIOMAS AND GLIOBLASTOMA-DERIVED SPHERES

Yoshimoto, K., Murata, H., Hatae, R., Akagi, Y., Mizoguchi, M., Iihara, K.

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2014

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english

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4

CLONAL EVOLUTION OF GLIOMAS IS ENCODED IN THE EVOLUTIONARY DYNAMICS OF DNA METHYLATION

Costello, J. F., Mazor, T., Pankov, A., Johnson, B. E., Hong, C., Bell, R. J. A., Smirnov, I. V., Reis, G. F., Phillips, J. J., Barnes, M., Bollen, A. W., Taylor, B. S., Molinaro, A. M., Olshen, A. B.

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Year:

2014

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english

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5

MUTATION-BASED MOLECULAR GLIOMA CLASSIFICATION: PREVALENCE AND ASSOCIATION WITH GERMLINE RISK SNPS

Jenkins, R. B., Decker, P., Kosel, M., Eckel-Passow, J., Walsh, K. M., Smirnov, I. V., Caron, A., Kollmeyer, T., Rice, T., Hansen, H. M., Molinaro, A. M., McCoy, L. S., Bracci, P. M., Cabriga, B. S.,

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2014

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english

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6

MUTANT IDH1 SUPPRESSES APOPTOSIS REGULATOR PAR-4 IN GLIOMAS

Horbinski, C., Liu, Y., Gilbert, M. R., Kyprianou, N.

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2014

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english

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7

NOVEL APPROACH TO MODEL BRAIN TUMOURS BY INDUCING LOCALLY RESTRICTED AND STEM CELL SELECTIVE GENE TARGETING

Brandner, S., Benedykcinska, A., Li, N., Henriquez, N.

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2014

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english

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8

DIRECT CELL CONTACT BETWEEN BRAIN ENDOTHELIAL CELLS AND GLIOMA STEM CELLS PROMOTES ENDOTHELIAL CELL MIGRATION

Gladson, C. L., Burgett, M. E., Lathia, J. D., Roth, P., Huang, P., Vasanji, A., Li, M., Bao, S., Nowacki, A., RIch, J. N., Weller, M.

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2014

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english

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9

ERBB2/HER2-SPECIFIC NATURAL KILLER CELLS FOR ADOPTIVE IMMUNOTHERAPY OF GLIOBLASTOMA

Steinbach, J. P., Zhang, C., Burger, M., Jennewein, L., Schonfeld, K., Genssler, S., Sahm, C., Brendel, C., Naundorf, S., Odendahl, M., Kohl, U., Nowakowska, P., Seifried, E., Bonig, H., Tonn, T., Gre

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2014

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10

A NOVEL P53 BYSTANDER EFFECT INDUCES GLIOBLASTOMA CELL DEATH THROUGH A GLYCOSYLATION-DEPENDENT MECHANISM

Van Meir, E. G., Lee, S.-H., Khwaja, F. W., Zerrouqi, A., Zhang, Z., Olson, J. J., Kaluzova, M., Hadjipanayis, C. G., Devi, N. S.

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2014

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english

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11

MUTANT EGFR SUPPRESSION OF MICRORNA-9 INDUCES FOXP1 TO ENHANCE GLIOBLASTOMA TUMORIGENICITY

Furnari, F., Gomez, G., Volinia, S., Croce, C., Zanca, C., Li, M., Gutmann, D., Brennan, C., Cavenee, W.

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2014

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12

PHASE II TRIAL OF THE PHOSPHATIDYINOSITOL-3 KINASE (PI3K) INHIBITOR BUPARLISIB (BKM120) IN RECURRENT GLIOBLASTOMA CONDUCTED BY THE IVY FOUNDATION EARLY PHASE CLINICAL TRIALS CONSORTIUM

Wen, P. Y., Wen, P. Y., Yung, W. K. A., Mellinghoff, I. K., Ramkissoon, S., Alexander, B., Rinne, M., Colman, H., Omuro, A. M., DeAngelis, L. M., Gilbert, M. R., DeGroot, J., Cloughesy, T. F., Lee, E.

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2014

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english

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13

TELOMERE LENGTH VARIANTS ARE ASSOCIATED WITH HIGH-GRADE GLIOMA RISK: IDENTIFICATION OF A NOVEL GLIOMA RISK LOCUS BY GENOME-WIDE ASSOCIATION STUDY

Walsh, K. M., Walsh, K. M., Codd, V., Smirnov, I. V., Rice, T., Decker, P. A., Hansen, H. M., Kollmeyer, T., Kosel, M. L., Molinaro, A. M., McCoy, L. S., Bracci, P. M., Cabriga, B. S., Pekmezci, M., Z

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2014

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english

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14

MOVING BEYOND VEGF: INHIBING GLIOMA ANGIOGENESIS BY TARGETING THE TIE2/ANGIOPOIETIN SIGNALING PATHWAY

Plate, K. H., Scholz, A., Mittelbronn, M., Harter, P., Dumont, D., van Slyke, P., Reiss, Y.

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2014

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english

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15

INFORMATION-GUIDED SURGERY USING INTRAOPERATIVE MRI AND FUNCTIONAL MAPPING FOR GLIOMAS.

Muragaki, Y., Iseki, H., Maruyama, T., Suzuki, T., Yoshimitsu, K., Chernov, M., Ikuta, S., Tamura, M., Okamoto, J., Hayashi, M., Okada, Y.

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2014

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16

NEXT-GENERATION NEUROPATHOLOGY - IMPROVING DIAGNOSTIC ACCURACY FOR BRAIN TUMORS USING DNA METHYLATION ARRAY-BASED MOLECULAR PROFILING

Jones, D. T. W., Capper, D., Sill, M., Hovestadt, V., Lichter, P., Zagzag, D., Karajannis, M. A., Aldape, K. D., Korshunov, A., von Deimling, A., Pfister, S. M.

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2014

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english

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17

MOLECULAR MOTORS AS NOVEL TARGETS TO BLOCK GLIOMA DISPERSION AND PROLIFERATION

Rosenfeld, S. S., Venere, M., Lammerding, J., Ivkovic, S., Amendolara, B., Crish, J., Picariello, H., Rich, J., Canoll, P.

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2014

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english

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18

DETAILED MOLECULAR CHARACTERISATION OF DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIES THREE MOLECULAR SUBGROUPS AND A NOVEL CANCER DRIVER, ACVR1

Hawkins, C., Buczkowicz, P., Hoeman, C., Rakopoulos, P., Pajovic, S., Morrison, A., Jones, C., Bouffet, E., Bartels, U., Becher, O.

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2014

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english

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19

IDENTIFICATION AND PRELIMINARY TREATMENT DATA OF XENOGRAFTS REPRESENTING TCGA-DEFINED SUBTYPES

Keir, S. T., Roskoski, M. A., Gasinski, D., Kwatra, M. K., Friedman, H. S., Bigner, D. D.

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2014

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english

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20

GENOME-WIDE ANALYSIS UNCOVERS RECURRENT ALTERATIONS IN PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMAS (PCNSL)

Patrick O'Neill, B., Braggio, E., O'Neill, B. P., Van Wier, S., Ojha, J., McPhail, E., Asmann, Y., Egan, J., Ayres da Silva, J., Schiff, D., Lopes, M. B., Valdez, R., Tibes, R., Eckloff, B., Stewart,

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2014

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english

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21

INTRA-OPERATIVE MAPPING OF NEURAL NETWORKS DURING AWAKE CRANIOTOMY FOR RESECTION OF BRAIN TUMORS: WORK IN PROGRESS

Ram, Z., Gonen, T.

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2014

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english

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22

MTOR KINASE INHIBITORS AND APOPTOSIS IN GLIOBLASTOMA

Weiss, W. A., Wong, R., Fan, Q.-W., Ilkhanizadeh, S., Lu, M., Beyer, J., Dube, N., Forsayeth, J., Kells, A., Xu, T., Bankiewicz, K., Ducker, G., Feldman, M., Shokat, K.

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2014

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english

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23

THE P53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA

Verhaak, R. G. W., Kim, H., Zheng, S., Amini, S. S., Virk, S. M., Mikkelsen, T., Brat, D. J., Grimsby, J., Sougnez, C., Muller, F., Hu, J., Sloan, A. E., Cohen, M. L., Van Meir, E. G., Scarpace, L., L

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2014

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english

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24

CONVECTION-ENHANCED DELIVERY OF NIMUSTINE HYDROCHLORIDE FOR BRAINSTEM MALIGNANT GLIOMA: CURRENT STUDY AND DEVELOPMENT OF NEW DEVICE

Saito, R., Sonoda, Y., Tominaga, T.

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2014

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english

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25

HISTONE DEACETYLASE INHIBITOR PCI-24781 SHOWS ANTIPROLIFERATIVE EFFECTS AGAINST PEDIATRIC GLIOBLASTOMA CELLS

Valera, E. T., Andrade, P. V., Andradre, A. F., Queiroz, R. G. d. P., Scrideli, C. A., Tone, L.

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2014

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english

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26

PROGNOSTIC FACTORS FOR PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMAS TREATED WITH HIGH-DOSE METHOTREXATE-BASED CHEMO-RADIOTHERAPY

Nagane, M., Lee, J., Shishido-Hara, Y., Suzuki, K., Shimizu, S., Umino, M., Kobayashi, K., Shiokawa, Y.

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2014

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english

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27

INTRACRANIAL GERM CELL TUMORS WITH MTOR MUTATION ARE COMMON IN BASAL GANGLIA

Nishikawa, R., Fukuoka, K., Ichimura, K.

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2014

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english

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28

PATIENT-DERIVED XENOGRAFTS MIRROR THE PROTEOMIC PROFILE OF HUMAN GLIOBLASTOMA: IMPLICATIONS FOR PERSONALIZED DRUG DEVELOPMENT

Kwatra, M. M., Brown, K. E., Chagoya, G., Keir, S. T., Bigner, D. D., Sampson, J. H.

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2014

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english

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29

ELUCIDATING THE ONCOGENIC ROLE OF ATRX DEFICIENCY IN GLIOMA

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2014

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english

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30

SINGLE CELL DERIVED CLONAL ANALYSIS OF HUMAN GLIOBLASTOMA LINKS FUNCTIONAL AND GENOMIC HETEROGENEITY

Dirks, P. B., Meyer, M., Reimand, J., Lan, X., Head, R., Zhu, X., Kushida, M., Bayani, J., Pressey, J. C., Lionel, A., Clarke, I. D., Cusimano, M., Squire, J., Scherer, S., Bernstein, M., Woodin, M. A

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2014

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english

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31

AN ALL HUMAN 3D IN VITRO MODEL OF THE BLOOD BRAIN BARRIER IN NANOPARTICLE DELIVERY AND CANCER METASTASIS STUDIES

Pilkington, G. J., Maherally, Z., Jassam, S., Barbu, E., Fillmore, H.

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2014

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english

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32

DEVELOPMENT OF NOVEL SMALL MOLECULES THAT TARGET GLIOBLASTOMA STEM CELLS

Kesari, S., Tsigelny, I. F., Mukthavaram, R., Kouznetsova, V. L., Chao, Y., Pastorino, S., Jiang, P., Pingle, S. C., Wrasidlo, W., Makale, M.

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2014

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english

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33

GLIOBLASTOMA STEM CELL-DERIVED PERICYTES AND TUMOR ANGIOGENESIS

Bao, S., Cheng, L., Huang, Z., Zhou, W., Wu, Q., Rich, J. N.

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2014

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english

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34

RANDOMIZATION OF PATIENTS WITH GLIOBLASTOMA TO VACCINE SITE PRE-CONDITIONING WITH TETANUS-DIPHTHERIA TOXOID SYSTEMICALLY ENHANCES MIGRATION AND THERAPEUTIC EFFECT OF CYTOMEGALOVIRUS PP65-PULSED DENDRITIC CELL VACCINE IN A MIP-1 -DEPENDENT FASHION

Sampson, J., Mitchell, D. A., Batich, K. A., Snyder, D., Xie, W., Reap, E., Cui, X., Sanchez-Perez, L., Archer, G. E., Nair, S. K., Gunn, M. D.

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2014

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english

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35

ABCG2 AND MDR PROMOTE BRAINSTEM GLIOMAGENESIS AND LIMIT THE EFFICACY OF DASATINIB IN A DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) MOUSE MODEL

Becher, O. J., Mittapali, R., Chung, A. H., Crabtree, D., Elmquist, W.

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2014

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english

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36

HIGH-THROUGHPUT SCREENING OF GLIOMA STEM CELL LINES FOR DRUG STRUCTURE- AND GENOTYPE-CORRELATED SENSITIVITY TO A PANEL OF TYROSINE KINASE INHIBITORS

de Groot, J., Thomas, C., Piao, Y., Nguyen, N., Drewry, D., Zuercher, B., Verhaak, R., Stephan, C., Sulman, E. P., Lang, F., Yung, A.

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2014

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english

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37

GENETIC AND HISTOLOGICAL STABILITY OF OLIGODENDROGLIAL TUMORS WITH 1P/19Q CO-DELETION EVEN AFTER CHEMOTHERAPY AND OR RADIATION THERAPY

Ueki, K., Aihara, K., Mukasa, A., Higuchi, F., Matsuda, H., Kim, P.

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Year:

2014

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english

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38

ONCOLYTIC POLIOVIRUS IMMUNOTHERAPY OF GLIOBLASTOMA

Gromeier, M., Dobrikova, E., Dobrikov, M., Brown, M., Bryant, J., Threatt, S., Boulton, S., Carter, K., Herndon, J., Desjardins, A., Friedman, H., Sampson, J., Friedman, A., Bigner, D.

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2014

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english

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39

INFLUENCE OF DRUG DELIVERY ON THERAPEUTIC BENEFIT IN GBM-CDK4 AND MDM2 INHIBITOR COMPARISON IN FLANK VERSUS ORTHOTOPIC MODELS AND COMPARISON OF BRAIN PENETRANT VERSUS IMPENETRANT PI3K/MTOR INHIBITORS

Sarkaria, J. N., Pokorny, J. L., Mladek, A. C., Parrish, K., Oberoi, R., Sio, T., Mittapalli, R. K., Elmquist, W. F.

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2014

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english

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40

RESULTS OF THE INTERNATIONAL INTERLABORATORY COMPARISON OF MGMT PROMOTER METHYLATION ANALYSIS INVOLVING TWENTY-THREE ACADEMIC CENTERS IN GERMANY, AUSTRIA AND THE NETHERLANDS

Reifenberger, G., Malzkorn, B., Acker, T., Bettstetter, M., Buslei, R., von Deimling, A., Dietmaier, W., Dubbink, H. J., Eigenbrod, S., Garvalov, B. K., Gerstenmaier, U., Giese, A., Haase, D., Hasselb

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2014

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english

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41

METASTASIS AND TUMOR RECURRENCE FROM RARE SOX9-POSITIVE CELLS IN MYCN-DRIVEN MEDULLOBLASTOMA

Swartling, F. J., Savov, V., an er, M., Bolin, S., Fotaki, G., Dubuc, A., Remke, M., Ramaswamy, V., Weishaupt, H., Taylor, M. D.

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2014

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english

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42

MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS

Kool, M., Sturm, D., Northcott, P. A., Jones, D. T. W., Korshunov, A., Lichter, P., Pfister, S.

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2014

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english

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43

"GO OR GROW" - LINKS BETWEEN CELLULAR FUNCTION, GLUCOSE METABOLISM AND GLIOMA MICROENVIRONMENT

Lamszus, K., Kathagen, A., Holz, M., Schulte, A., Westphal, M.

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2014

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english

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44

UNDERSTANDING AND TACKLING THE TUMOR-IMMUNE CELL DIALOGUE DURING PROGRESSION AND THERAPEUTIC RESISTANCE

Bergers, G., Lu, K., Rivera, L.

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2014

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english

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45

TARGETING RESISTANCE PATHWAYS IN BRAF-MUTANT PEDIATRIC GLIOMAS

Nicolaides, T., Yao, T. W., Yoshida, Y., Zhang, J., Ozawa, T., James, D.

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2014

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english

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46

PRE-OPERATIVE CHEMOTHERAPY AS A NEW STRATEGY OF TREATMENT FOR LOW GRADE GLIOMAS IN ELOQUENT AREAS

Ruda, R., Bello, L., Castellano, A., Bertero, L., Trevisan, E., Riva, M., Falini, A., Soffietti, R.

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2014

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english

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47

ONCOLYTIC POLIO/RHINOVIRUS RECOMBINANT (PVSRIPO) IN RECURRENT GLIOBLASTOMA (GBM): FIRST PHASE I CLINICAL TRIAL EVALUATING THE INTRATUMORAL ADMINISTRATION

Desjardins, A., Sampson, J. H., Peters, K. B., Ranjan, T., Vlahovic, G., Threatt, S., Herndon, J. E., Boulton, S., Lally-Goss, D., McSherry, F., Friedman, A. H., Friedman, H. S., Bigner, D. D., Gromei

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Year:

2014

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english

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48

VASCULOGENESIS IN VON HIPPEL-LINDAU DISEASE ASSOCIATED TUMORS

Lonser, R. R., Frerich, J., Huntoon, K., Yang, C., Merrill, M., Abdullaev, Z., Pack, S., Shively, S., Stamp, G., Zhuang, Z.

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2014

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english

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49

EPIGENETIC REGULATION OF GBM CELL STEMNESS AND TUMOR PROPAGATING CAPACITY BY OCT4 AND SOX2

Laterra, J., Lopez-Bertoni, H., Lal, B., Li, A., Caplan, M., Guerrero-Cazares, H., Eberhart, C. G., Quinones-Hinojosa, A., Li, Y.

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Year:

2014

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english

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50

IDH1 MUTATIONS AS A IMMUNOTHERAPEUTIC TARGET FOR BRAIN TUMORS

Archer, G. E., Reap, E., Norberg, P., Cui, X., Schmittling, R., Herndon, J., Chandramohan, V., Riccione, K., Kuan, C.-T., Yan, H., Bigner, D. D., Sampson, J. H.

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2014

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english

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51

NEW GLIOMA-ASSOCIATED AUTO-ANTIBODIES

Fueyo, J., Conrad, C., Gomez-Manzano, C., Yung, W. A., Tufaro, F., Lang, F.

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2014

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english

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52

TARGET IDENTIFICATION IN GLIOMA INITIATING CELLS

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2014

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53

TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL

Yan, H., Killela, P. J., Reitman, Z. J., Jiao, Y., Bettegowda, C., Agrawal, N., Diaz, L. A., Friedman, A. H., Friedman, H., Gallia, G. L., Giovanella, B. C., Grollman, A. P., He, T. C., He, Y., Hruban

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2014

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english

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54

TERT PROMOTER MUTATIONS CONTRIBUTE TO PROGNOSTIC SUBGROUPS OF LOWER GRADE ASTROCYTOMAS

Ng, H. K., Chan, A., Yao, Y., Chan, D.

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2014

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english

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55

INTEGRATIVE GENOMIC CHARACTERIZATION OF LOWER GRADE GLIOMAS

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2014

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english

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56

INTERPLAY OF LIPID DROPLETS AND AUTOPHAGY REGULATES GLIOBLASTOMA SURVIVAL

Guo, D., Geng, F., Aggarwal, R., Liu, J., Yoo, J. Y., Guo, Q., Guo, J. Y., Hurwitz, B., Ru, P., Cheng, C., Joshi, K., Ichiro, N., Kaur, B., Chakravarti, A.

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2014

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english

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57

NEO212: A NOVEL TEMOZOLOMIDE-PERILLYL ALCOHOL CONJUGATE EXHIBITS SUPERIOR ACTIVITY AGAINST TEMOZOLOMIDE RESISTANT GLIOMAS AND INTRACRANIAL TRIPLE NEGATIVE BREAST CANCER METASTASIS

Chen, T. C., Schonthal, A. H., Hofman, F. M., Wang, W., Cho, H.

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2014

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english

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58

IMAGING BIOMARKERS OF MALIGNANT PROGRESSION OF DIFFUSE LOW-GRADE GLOMA (LGG)

Chang, S. M., Elkhaled, A., Jalbert, L., Phillips, J. J., Cha, S., Molinaro, A., Nelson, S. J.

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2014

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english

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59

GLIOMA SPECIFIC PEPTIDES: A PLATFORM FOR MOLECULAR IMAGING AND THERAPEUTIC TARGETING

Senger, D. L., Rahn, J. J., Hao, X., Lun, X. W. X., Cairncross, J. G., Weiss, S., Venugopal, C., McFarlane, N. M., Singh, S. K., Robbins, S. M., Senger, D. L.

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2014

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english

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60

FUNCTIONAL PRESENCE OF M2 MACROPHAGE MARKERS IN GBM TUMOR CELLS

Debinski, W., Rodriguez, A., Gibo, D., Tatter, S. B., Mott, R., Lively, M., Miller, L., Seals, D. F.

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2014

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english

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61

HIGHLY SELECTIVE INTRA-ARTERIAL CHEMOTHERAPY FOR THE TREATMENT OF PROGRESSIVE DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPG)

Cohen, K. J., Jones, A., Raabe, E., Pearl, M.

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2014

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english

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62

A "PRECISION MEDICINE" STRATEGY FOR RECURRENT GLIOBLASTOMA

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2014

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63

MRE11-RAD50-NBS1 COMPLEX INHIBITOR MIRIN ENHANCES RADIOSENSITIVITY IN HUMAN GLIOBLASTOMA CELLS

Mishima, K., Mishima-Kaneko, M., Kawata, T., Saya, H., Ishimaru, N., Yamada, K., Nishikawa, R., Shigematsu, N.

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Year:

2014

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64

MAPPING THE GLIOBLASTOMA METABOLOME AFTER BEVACIZUMAB THERAPY BY 13C6-GLUCOSE METABOLOMIC FLUX ANALYSIS.

Bjerkvig, R., Fack, F., Frezza, C., Keunen, O., Stieber, D., Lund-Johansen, M., Miletic, H., Gottlieb, E., Niclou, S. P.

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Year:

2014

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english

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65

MIF-CD74 GUIDED THERAPEUTIC STRATEGY FOR THE UPFRONT TREATMENT OF GBM PATIENTS WITH AN UNMETHYLATED MGMT PROMOTER

McDonald, K. L., Ha, W., Sevim, H.

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Year:

2014

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english

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66

FIRST-IN-HUMAN PHASE I CLINICAL TRIAL OF ONCOLYTIC DELTA-24-RGD (DNX-2401) WITH BIOLOGICAL ENDPOINTS: IMPLICATIONS FOR VIRO- IMMUNOTHERAPY

Lang, F. F., Conrad, C., Gomez-Manzano, C., Tufaro, F., Yung, W., Sawaya, R., Weinberg, J., Prabhu, S., Fuller, G., Aldape, K., Fueyo, J.

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Year:

2014

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english

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67

EPHRINA2 RECEPTOR IN HUMAN GLIOBLASTOMA CANCER STEM CELLS AND IDENTIFICATION OF NEW, PUTATIVE THERAPEUTIC TARGETS

Vescovi, A. L., Binda, E., Mazza, T., Dimeco, F.

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Year:

2014

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english

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68

RB1 SUPPRESSION IS RESPONSIBLE FOR ACQUIRED CDK4/6 INHIBITOR RESISTANCE IN GLIOBLASTOMA

James, C. D., Lu, Y.-J., Ozawa, T., Prados, M. D., Waldman, T.

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Year:

2014

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english

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69

TRANSCRIPTIONAL REGULATION OF OLIGODENDROGLIAL CELL FATE BY DLX HOMEOBOX GENES: POTENTIAL RELEVANCE TO HISTONE H3.3 MUTATIONS IN PEDIATRIC HIGH GRADE GLIOMA

Eisenstat, D. D., Zagozewski, J., Ziegler, K., Japoni, S., Jiang, Q., Underhill, D. A.

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Year:

2014

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english

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70

GENETIC CHANGES IN RADIATION-ASSOCIATED MENINGIOMA

Claus, E. B., Calvocoressi, L., Greenhalgh, S., Walsh, K., Schildkraut, J., Bondy, M., Wiemels, J., Wrensch, M., Al-Mefty, O., Townsend, J.

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Year:

2014

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71

ASSOCIATION OF MATRIX METALLOPROTEINASE 2 (MMP2) BASELINE PLASMA LEVEL WITH RESPONSE AND SURVIVAL AND CHANGE OVERTIME IN PATIENTS TREATED WITH BEVACIZUMAB FOR RECURRENT HIGH GRADE GLIOMA

Chinot, O.-L., Boudouresque, F., Barrie, M., Matta, M., Boucard, C., Loundou, A., Figarella-Branger, D., Ouafik, L., Tabouret, E.

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Year:

2014

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72

THE WARBURG EFFECT AND BEYOND

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2014

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english

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73

PROGNOSTIC AND PREDICTIVE BIOMARKER-BASED SUBGROUPS IN THE NOA-04 TRIAL

Wick, W., Wiestler, B., Capper, D., Sill, M., Hovestadt, V., Schliesser, M. G., Weiss, E., Jones, D. T. W., Roth, P., Pfister, S. M., Korshunov, A., Platten, M., Reifenberger, G., von Deimling, A., We

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Year:

2014

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english

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74

TEMPORAL AND SPACIAL EVOLUTION OF CLONES IN 400 LOW GRADE GLIOMAS IN JAPAN

Natsume, A., Suzuki, H., Ogawa, S., Wakabayashi, T.

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Year:

2014

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75

COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS AND NOVEL TARGETS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS

Kaplan, D., Grinshtein, N., Rioseco, C., Luchman, A., Datti, A., Aman, A., Uehling, D., Prakesch, M., Wrana, J., Cairncross, G., Shen, Y., Jones, S., Marra, M., Senger, D., Robbins, S., Al-Awar, R., M

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Year:

2014

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english

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76

BRAIN TUMOUR INITIATING CELLS AND TARGETING STAT3 ONCOGENIC SIGNALLING IN GBM

Weiss, S., Nguyen, S., Luchman, A., Grinshtein, N., Stechishin, O., Aman, A., Uehling, D., al-Awar, R., Kaplan, D.

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Year:

2014

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english

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77

TARGETING GLIOMA INITIATING CELLS IN GBM: ABTC-0904, A RANDOMIZED PHASE 0/II STUDY TARGETING THE SONIC HEDGEHOG-SIGNALING PATHWAY

Sloan, A. E., Nock, C. J., Supko, J., Ye, X., Takebe, N., Rich, J., Prados, M., Grossman, S.

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Year:

2014

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english

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78

MODELLING HIGH MYC MEDULLOBLASTOMA AND OTHER BRAIN TUMORS USING HUMAN NEURAL STEM CELLS

Eberhart, C., Raabe, E., Hanaford, A., Pomeroy, S.

Journal:

Year:

2014

Language:

english

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79

CYTOMEGALOVIRUS CONTRIBUTES TO GLIOBLASTOMA IN THE CONTEXT OF TUMOR SUPPRESSOR MUTATIONS

Chiocca, E. A., Price, R. L., Hollon, T., Alvarez-Breackenridge, C., Fernandez, S., Oglesbee, M., Cook, C., Lawler, S., Kwon, C.-H.

Journal:

Year:

2014

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english

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80

REAL-TIME ATLAS-BASED STEREOTACTIC NEURONAVIGATION

Prabhu, S., Vabulas, M., Kumar, V. A., Hamilton, J. D., Martinez, J. J., Rao, G., Sawaya, R.

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Year:

2014

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english

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81

INCIDENCE AND OUTCOMES IN GLIOMAS FROM BRAIN TUMOR REGISTRY OF JAPAN 2001-2004

Narita, Y., Shibui, S.

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Year:

2014

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english

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82

PID1 IS A NOVEL SENSITIZER OF BRAIN TUMOR CELLS TO CHEMOTHERAPY

Erdreich-Epstein, A., Xu, J., Ren, X.

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Year:

2014

Language:

english

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83

FORETINIB IS EFFECTIVE THERAPY FOR METASTATIC SONIC HEDGEHOG MEDULLOBLASTOMA

Smith, C., Faria, C. C., Dubuc, A. M., Remke, M., Golbourn, B. J., Diaz, R. J., Agnihotri, S., Luck, A., Sabha, N., Olsen, S., Wu, X., Garzia, L., Ramaswamy, V., Mack, S. C., Wang, X., Leadley, M., Re

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Year:

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84

TEMOZOLOMIDE FOR RECURRENT INTRACRANIAL EPENDYMOMA OF THE ADULT: PATTERNS OF RESPONSE, SURVIVAL AND CORRELATIONS WITH MGMT PROMOTER METHYLATION

Soffietti, R., Bosa, C., Bertero, L., Trevisan, E., Cassoni, P., Morra, I., Ruda, R.

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Year:

2014

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english

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85

EFFECT OF TEMOZOMIDE ON HUMAN DENDRITIC CELLS

Asai, A., Iwata, R., Ito, T., Oshige, H., Yoshimura, K., Takeda, J.-i.

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Year:

2014

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english

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86

NEXT-GENERATION RECOMBINANT IMMUNOTOXINS FOR GLIOBLASTOMAS AND MELANOMAS TREATMENT

Kuan, C.-T., Pastan, I. H., Bigner, D. D.

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Year:

2014

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87

COMPLEX EVOLUTIONARY DYNAMICS GENERATES GENETIC DIVERSITY AND INTRA-TUMOR HETEROGENEITY IN INDIVIDUAL PATIENTS WITH GLIOBLASTOMA

Watts, C., Piccirillo, S., Spiteri, I., Sottoriva, A., Touloumis, A., Marioni, J., Curtis, C., Tavare, S.

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Year:

2014

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88

THE TREATMENT-RESISTANT MESENCHYMAL SIGNATURE IN GLIOBLASTOMA DERIVES FROM TUMOR CELLS INDEPENDENT OF STROMA

Sulman, E. P., Wang, Q., Ezhilarasan, R., Goodman, L. D., Gumen, J., Sun, P., Aldape, K., Alfred Yung, W., Heffernan, T., Draetta, G. F., Lang, F. F.

Journal:

Year:

2014

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english

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89

EVEROLIMUS (RAD001) AND THE MTOR PATHWAY IN LOW-GRADE GLIOMAS

Clarke, J. L., Chang, S., Phillips, J., Molinaro, A., Berger, M., Nelson, S., Haas-Kogan, D.

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Year:

2014

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english

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90

PROGNOSTIC VALUE OF O-(2-[18F]FLUORETHYL)-L-TYROSINE POSITRON EMISSION TOMOGRAPHY (18FET-PET) WITHIN THE CLINICAL COURSE IN NEWLY DIAGNOSED GLIOBLASTOMA

Tonn, J. C., Suchorska, B., Jansen, N. L., Linn, J., Kretzschmar, H., Janssen, H., Eigenbrod, S., Simon, M., Popperl, G., Kreth, F. W., la Fougere, C., Weller, M.

Journal:

Year:

2014

Language:

english

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91

INITIAL SYMPTOMS OF PINEAL REGION TUMORS - COMPARISON TO HISTORICAL CONTROL OF PRE-CT ERA -

Fujimaki, T., Fukuoka, K., Shirahata, M., Suzuki, T., Adachi, J.-i., Yanagisawa, T., Mishima, K., Wakiya, K., Matsutani, M., Nishikawa, R.

Journal:

Year:

2014

Language:

english

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92

FUNCTION OF ECOTROPIC VIRAL INTEGRATION SITE 1 (EVI1) GENE IN MOUSE NEURAL PRECURSOR CELLS AND HUMAN GLIOMA INITIATING CELLS

Takeshima, H., Yokogami, K., Mizuguchi, A., Yamasaki, K., Kawasoe, T., Morishita, K.

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Year:

2014

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english

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93

WHOLE EXOME SEQUENCING IDENTIFIED THAT THE MAPK AND PI3K PATHWAYS ARE THE MAIN TARGETS FOR MUTATIONS IN INTRACRANIAL GERM CELL TUMORS

Ichimura, K., Fukushima, S., Totoki, Y., Matsushita, Y., Otsuka, A., Tomiyama, A., Niwa, T., Sakai, R., Ushijima, T., Nakamura, T., Suzuki, T., Fukuoka, K., Yanagisawa, T., Mishima, K., Nakazato, Y.,

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Year:

2014

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94

GENETIC AND EPIGENETIC DEREGULATION ARE ASSOCIATED WITH THE ABERRANT EXPRESSION OF A STEM CELL RELATED HOX GENE SIGNATURE IN GLIOBLASTOMA

Hegi, M. E., Kurscheid, S., Sciuscio, D., Samarzija, I., Stupp, R., Delorenzi, M.

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Year:

2014

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95

TREE DERIVED SURVIVAL RISK GROUPS IN DIFFERENTIATING RISK FOR GLIOMA PATIENTS

Molinaro, A. M., Olshen, A., Strawderman, R.

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Year:

2014

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2014

96

INTEGRATION OF CANCER STEM CELL MAINTENANCE AND LIPID METABOLISM BY SCAVENGER RECEPTORS

Lathia, J. D., Hale, J. S., Sloan, A. E., Gladson, C. L., Hazen, S. L., Horbinski, C., Rich, J. N., Brown, J. M.

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Year:

2014

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97

A NOVEL POLYCOMB FEED FORWARD LOOP IN GLIOBLASTOMA MULTIFORME

Marino, S., Ricci, B., Greco, A., Acquati, S.

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2014

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98

THOR METHYLATION PROVIDES INSIGHT INTO THE TELOMERE MAINTENANCE LANDSCAPE OF MALIGNANT GLIOMAS

Tabori, U., Castelo-Branco, P., Lee, D., Gallo, M., Limpan, T., Mangerel, J., Price, A., Remke, M., Zhang, C., Heidari, A., Wani, K., Vanner, R., Zadeh, G., Karamchandani, J., Das, S., Taylor, m., Haw

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Year:

2014

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99

WT1 PEPTIDE VACCINATION FOR MALIGNANT GLIOMAS AS A PART OF MULTI-MODAL THERAPY

Hashimoto, N., Tsuboi, A., Chiba, Y., Hirayama, R., Takano, K., Kijima, N., Oka, Y., Kagawa, N., Izumoto, S., Sugiyama, H., Yoshimine, T.

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Year:

2014

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100

GLIOMAS PROMOTE INDUCTION OF B7-H1/PD-L1 EXPRESSION ON MONOCYTES: CLINICAL EVIDENCE OF AN IMMUNOSUPPRESSIVE MECHANISM THAT CAN BE TARGETED WITH ANTIBODY BLOCKADE

Parsa, A. T., Bloch, O., Crane, C., Kaur, R., Safae, M.

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Year:

2014

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101

A PHASE III RANDOMIZED CONTROLLED TRIAL OF SHORT-COURSE RADIOTHERAPY WITH OR WITHOUT CONCOMITANT AND ADJUVANT TEMOZOLOMIDE IN ELDERLY PATIENTS WITH GLIOBLASTOMA (NCIC CTG CE.6, EORTC 26062-22061, TROG 08.02, NCT00482677)

MD, J. R. P., O'Callaghan, C. J., Ding, K., Roa, W., Mason, W. P., Cairncross, J. G., Brandes, A. A., Menten, J., Phillips, C., Fay, M. F., Nishikawa, R., Winch, C., Laperriere, N.

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Year:

2014

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2014

102

NK CELLS FROM GLIOMA-BEARING MICE TREATED WITH TEMOZOLOMIDE ARE ENRICHED FOR GENES RELATED TO MULTI-DRUG RESISTANCE AND CHEMOTAXIS

Pellegatta, S., Pessina, S., Cantini, G., Kapetis, D., Cazzato, E., Finocchiaro, G.

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Year:

2014

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2014

103

REPEATED INTRANASAL APPLICATION OF NEURAL STEM CELL-MEDIATED ENZYM/PRODRUG THERAPY USING A NOVEL HSV-THYMIDINE KINASE VARIANT IMPROVES THERAPEUTIC EFFICIENCY IN AN INTRACRANIAL GLIOBLASTOMA MODEL

Schmidt, N. O., Duhrsen, L., Reitz, M., Henze, M., Sedlacik, J., Riecken, K., Fehse, B., Westphal, M.

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Year:

2014

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2014

104

METABOLIC IMAGING BIOMARKERS FOR MUTANT IDH1 GLIOMAS

Ronen, S. M., Izquierdo-Garcia, J. L., Chaumeil, M. M., Cai, L. M., Phillips, J. J., Pieper, R. O.

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Year:

2014

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english

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105

POTENCY OF SECRETING HCG- IN GERMINOMAS. CLINICAL AND BIOLOGICAL ANALYSIS

Matsutani, M., Takami, H., Fukuoka, K., Mishima, K., Nishikawa, R., Icimura, K.

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Year:

2014

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english

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106

A C-MET-ss1 INTEGRIN COMPLEX DRIVES INVASIVE RESISTANCE TO ANTI-ANGIOGENIC THERAPY

Aghi, M. K., Jahangiri, A., Mascharak, S., De Lay, M.

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Year:

2014

Language:

english

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107

CONTEXT OF VULNERABILITY OF GBM: DESCRIPTIVE GENOMICS LEADING TO EMPIRIC THERAPEUTICS

Berens, M. E., Kim, S., Kiefer, J., Dhruv, H., Vuori, K., Findlay, B., Hauser, C., Oshima, R., Alza-Blanc, P., Emig, D.

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Year:

2014

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english

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108

EFFECTS OF SIMULATED MICROGRAVITY ON PROLIFERATION AND CHEMOSENSITIVITY IN MALIGNANT GLIOMA CELLS

Kurisu, K., Takeda, M., Okazaki, T., Kawahara, Y., Yuge, L.

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Year:

2014

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english

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109

BIOLOGICALLY-BASED THERAPEUTICS FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMAS

Gupta, N., Hashizume, R., Andor, N., Zhang, Z., Petritsch, C., Mueller, S., James, C. D.

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Year:

2014

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english

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110

DIFFERENT MECHANISMS OF TUMOR GROWTH INHIBITION BY BLOCKADE OF IGF-IR IN U87-INDUCED AND STEM-LIKE CELL-INDUCED GLIOBLASTOMAS

Westphal, M., Zamykal, M., Martens, T., Lamszus, K.

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Year:

2014

Language:

english

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111

MOLECULAR-GUIDED NEOADJUVANT APPROACH FOR CHEMOSENSITIVE GLIOMAS

Sasaki, H., Hirose, Y., Yazaki, T., Kimura, T., Fujiwara, H., Kitamura, Y., Katayama, M., Toda, M., Ohira, T., Yoshida, K.

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2014

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112

List-of-Sponsors

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2014

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2014

113

IDENTIFICATION OF PATIENTS WITH RECURRENT GBM THAT BENEFIT FROM BEVACIZUMAB

French, P., Erdem-Eraslan, L., Kros, J. M., Oosterkamp, H. M., Walenkamp, A. M. E., Beerepoot, L., Hanse, M., Buter, J., Honkoop, A., van der Holt, B., Vernhout, R. M., Sillevis Smitt, P. A. E., Taal,

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Year:

2014

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english

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114

IMAGE GUIDED RNA-SEQ REVEALS SUBTYPE-SPECIFIC PATTERNS AT THE INFILTRATIVE MARGINS OF GLIOBLASTOMA

Canoll, P., Sims, P., Gil, B., Pisapia, D., Malone, H., Goldstein, H., Lei, L., Sonabend, A., Yun, J., Samanamud, J., Sims, J., Teich, A., Sheth, S., McKhann, G., Sisti, M., Bruce, J.

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Year:

2014

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english

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115

ANNEXIN A2 REGULATES ANGIOGENESIS AND INVASION PHENOTYPES OF MALIGNANT GLIOMA

Ichikawa, T., Onishi, M., Kurozumi, K., Maruo, T., Inoue, S., Michiue, H., Yoshida, K., Fuji, K., Ishida, J., Shimazu, Y., Oka, T., Chiocca, E. A., Date, I.

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Year:

2014

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116

IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA

Niclou, S. P., Fack, F., Hochart, G., Oudin, A., Leenders, W., Gottlieb, E., Bjerkvig, R., Stauber, J.

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Year:

2014

Language:

english

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117

IMMUNE CHECKPOINT BLOCKADE FOR GLIOBLASTOMA: PRECLINICAL ACTIVITY OF SINGLE AGENT AND COMBINATORIAL THERAPY

Reardon, D. A., Gokhale, P., Ligon, K., Liao, X., Rodig, S., Zhou, J., Win, L., Hodi, F. S., Kohl, N. E., Freeman, G.

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Year:

2014

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118

PRESENCE OF A DISTINCTIVE MYELOID POPULATION IS ASSOCIATED WITH THE INVASIVE TUMOR PHENOTYPE OBSERVED AFTER ANTI-ANGIOGENESIS THERAPIES

Gomez-Manzano, C., Gabrusiewicz, K., Cortes-Santiago, N., Hossain, M. B., Conrad, C., Fuller, G., Aldape, K., Lang, F., Gilbert, M., Alfred Yung, W. K., Fueyo, J.

Journal:

Year:

2014

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119

PROCOAGULANT TISSUE FACTOR EXPRESSION IS LINKED TO DISTINCT SUBTYPES IN GLIOBLASTOMA AND PLAYS A ROLE IN TUMOR DORMANCY

RAK, J., Magnusa, N., Garniera, D., Meehana, B., McGrawa, S., Leea, T. H., Caronb, M., Bourqueb, G., Milsomc, C., Jabadoa, N., Traslera, J.

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2014

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english

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120

PROGNOSTIC MARKER ANALYSIS IN PEDIATRIC POSTERIOR FOSSA EPENDYMOMAS

McLendon, R. E., Lipp, E., Gururangan, S., Fuchs, H., Zagzag, D., Herndon, J., Healy, P.

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Year:

2014

Language:

english

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121

QUALITY OF LIFE OF EXTREMELY LONG-TIME SURVIVORS WITH GERMINOMA MAINLY TREATED WITH RADIOTHERAPY

Sugiyama, K., Kurisu, K., Yamasaki, F., Tominaga, A.

Journal:

Year:

2014

Language:

english

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122

IDENTIFYING DRUG COMPOUNDS TARGETING TUMOR METABOLISM IN GLIOBLASTOMAS

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123

TRANSCRIPTIONAL PROFILING OF GBM INVASIVE GENES IDENTIFIES EFFECTIVE INHIBITORS OF THE LIM KINASE-COFILIN PATHWAY

Rutka, J., Park, J.-B., Agnihotri, S., Golbourn, B., Bertrand, K., Luck, A., Sabha, N., Croul, S., Smith, C. A.

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Year:

2014

Language:

english

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124

MICRO RNA BASED STRATEGY FOR ENHANCING THE EFFECT OF ONCOLYTIC HSV-1 VIRUS THERAPY

Ino, Y., Ito, M., Todo, T.

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Year:

2014

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english

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125

BENEFICIAL OUTCOMES AFTER PCV PLUS RT IN OLIGODENDROGLIAL TUMORS ARE ASSOCIATED WITH DETECTION OR RISK OF AN IDH MUTATION

Cairncross, G., Wang, M., Jenkins, R., Shaw, E., Giannini, C., Brachman, D., Buckner, J., Fink, K., Souhami, L., Laperriere, N., Huse, J. T., Mehta, M.

Journal:

Year:

2014

Language:

english

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126

INTRAOPERATIVE CONTRAST ENHANCED ULTRASOUND IN BRAIN TUMOR SURGERY

DiMeco, F., Prada, F. U., Perin, A., Aiani, L., Martegani, A., Solbiati, L., Lamperti, M., Casali, C., Legnani, F., Mattei, L., Saladino, A., Saini, M.

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2014

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127

EPIGENOME ALTERATIONS DEFINE LETHAL CIMP POSITIVE EPENDYMOMAS OF INFANCY

Taylor, M. D., Mack, S., Witt, H., Dirks, P., Pfister, S., Korshunov, A.

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2014

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128

DISTINCT AND SEPARABLE ROLES FOR HISTONE METHYLTRANSFERASE EZH2 IN NEUROGENIC ASTROCYTES

Lim, D. A., Hwang, W. W., Salinas, R. D., Siu, J. J., Kelley, K. W., Delgado, R. N., Paredes, M. F., Alvarez-Buylla, A., Oldham, M. C., Lim, D. A.

Journal:

Year:

2014

Language:

english

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129

PHASE I INDIVIDUAL DOSE TITRATION TRIAL OF THE HUMAN CORTICOTROPIN-RELEASING FACTOR (HCRF), CORTICORELIN ACETATE INJECTION (XERECEPT) IN PEDIATRIC PATIENTS WITH PERITUMORAL EDEMA OF THE BRAIN

Goldman, S., Fangusaro, J., Lulla, R., Chi, S., Manley, P., Robison, N., Kroon, H.-A., Kieran, M.

Journal:

Year:

2014

Language:

english

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130

LONG-TERM OUTCOME OF CENTRALLY LOCATED LOW-GRADE GLIOMA IN CHILDREN

Terashima, K., Chow, K., Jones, J., Ahern, C., Jo, E., Ellezam, B., Paulino, A. C., Okcu, M. F., Su, J., Adesina, A., Mahajan, A., Dauser, R., Whitehead, W., Lau, C., Chintagumpala, M.

Journal:

Year:

2014

Language:

english

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131

HIGH-THROUGHPUT DRUG SCREENING IDENTIFIES HDAC INHIBITORS AS CANDIDATE THERAPEUTICS FOR MYC-DRIVEN MEDULLOBLASTOMA

Wechsler-Reya, R. J., Pei, Y., Liu, K.-W., Wang, J., Esparza, L. A., Maier, D. L., Li, X.-N., Cho, Y.-J.

Journal:

Year:

2014

Language:

english

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132

C19MC ONCOMIRS CONVERGE ON MULTIPLE CELL CYCLE REGULATORS TO MODULATE NEURAL DIFFERENTIATION AND THE TUMOR EPIGENOME

Huang, A., Sin-Chan, P., Jabado, N.

Journal:

Year:

2014

Language:

english

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133

TRAIL POTENTIATES PANOBINOSTAT CYTOTOXICITY IN GLIOBLASTOMA MULTIFORME (GBM) IN VITRO

Darling, J. L., Rowther, F. B., Armesilla, A. L., Dawson, T. P., Ashton, K., Warr, T.

Journal:

Year:

2014

Language:

english

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134

DECIPHERING INTRINSIC AND ADAPTIVE RESISTANCE TO PI3K PATHWAY INHIBITORS IN GLIOMA

Yung, W. K. A., Koul, D., Wu, S., Fu, J.

Journal:

Year:

2014

Language:

english

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135

CABOZANTINIB IS EFFECTIVE IN A SUBSET OF XENOGRAFT GBM TUMORS AND AFFECTS MULTIPLE SIGNALING PATHWAYS

Mikkelsen, T., deCarvalho, A. C., Arnold, K., Mueller, C., Petricoin, E. F., Poisson, L. M., Irtenkauf, S., Hasselbach, L.

Journal:

Year:

2014

Language:

english

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136

YAP IS A CRITICAL AND NOVEL REGULATOR OF MIGRATION AND INVASION AND PREDICTS POOR OUTCOME IN GLIOBLASTOMA

Quinones-Hinojosa, A., Shah, S. R., Park, J., Levchenko, A., Quinones-Hinojosa, A.

Journal:

Year:

2014

Language:

english

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137

THE IMPACT OF OXYGEN TENSION ON CD8+ T CELL FUNCTION AND INTERACTION WITH GLIOMA CELLS

Walker, P. R., de Silly, R. V., Derouazi, M.

Journal:

Year:

2014

Language:

english

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138

PROFICIENCY PERFORMANCE BENCHMARKS FOR REMOVAL OF SIMULATED BRAIN TUMORS USING NEUROTOUCH

Del Maestro, R., Al Zhrani, G., Azarnoush, H., Winkler-Schwartz, A., Alotaibi, F., Lajoie, S. P.

Journal:

Year:

2014

Language:

english

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139

GENETIC AND EPIGENETIC DEREGULATION ARE ASSOCIATED WITH THE ABERRANT EXPRESSION OF A STEM CELL RELATED HOX GENE SIGNATURE IN GLIOBLASTOMA

Hegi, M. E., Kurscheid, S., Sciuscio, D., Samarzija, I., Stupp, R., Delorenzi, M.

Journal:

Year:

2014

Language:

english

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140

TREE DERIVED SURVIVAL RISK GROUPS IN DIFFERENTIATING RISK FOR GLIOMA PATIENTS

Molinaro, A. M., Olshen, A., Strawderman, R.

Journal:

Year:

2014

Language:

english

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141

INTEGRATION OF CANCER STEM CELL MAINTENANCE AND LIPID METABOLISM BY SCAVENGER RECEPTORS

Lathia, J. D., Hale, J. S., Sloan, A. E., Gladson, C. L., Hazen, S. L., Horbinski, C., Rich, J. N., Brown, J. M.

Journal:

Year:

2014

Language:

english

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142

A NOVEL POLYCOMB FEED FORWARD LOOP IN GLIOBLASTOMA MULTIFORME

Marino, S., Ricci, B., Greco, A., Acquati, S.

Journal:

Year:

2014

Language:

english

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143

THOR METHYLATION PROVIDES INSIGHT INTO THE TELOMERE MAINTENANCE LANDSCAPE OF MALIGNANT GLIOMAS

Tabori, U., Castelo-Branco, P., Lee, D., Gallo, M., Limpan, T., Mangerel, J., Price, A., Remke, M., Zhang, C., Heidari, A., Wani, K., Vanner, R., Zadeh, G., Karamchandani, J., Das, S., Taylor, m., Haw

Journal:

Year:

2014

Language:

english

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144

WT1 PEPTIDE VACCINATION FOR MALIGNANT GLIOMAS AS A PART OF MULTI-MODAL THERAPY

Hashimoto, N., Tsuboi, A., Chiba, Y., Hirayama, R., Takano, K., Kijima, N., Oka, Y., Kagawa, N., Izumoto, S., Sugiyama, H., Yoshimine, T.

Journal:

Year:

2014

Language:

english

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145

GLIOMAS PROMOTE INDUCTION OF B7-H1/PD-L1 EXPRESSION ON MONOCYTES: CLINICAL EVIDENCE OF AN IMMUNOSUPPRESSIVE MECHANISM THAT CAN BE TARGETED WITH ANTIBODY BLOCKADE

Parsa, A. T., Bloch, O., Crane, C., Kaur, R., Safae, M.

Journal:

Year:

2014

Language:

english

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146

A PHASE III RANDOMIZED CONTROLLED TRIAL OF SHORT-COURSE RADIOTHERAPY WITH OR WITHOUT CONCOMITANT AND ADJUVANT TEMOZOLOMIDE IN ELDERLY PATIENTS WITH GLIOBLASTOMA (NCIC CTG CE.6, EORTC 26062-22061, TROG 08.02, NCT00482677)

MD, J. R. P., O'Callaghan, C. J., Ding, K., Roa, W., Mason, W. P., Cairncross, J. G., Brandes, A. A., Menten, J., Phillips, C., Fay, M. F., Nishikawa, R., Winch, C., Laperriere, N.

Journal:

Year:

2014

Language:

english

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147

NK CELLS FROM GLIOMA-BEARING MICE TREATED WITH TEMOZOLOMIDE ARE ENRICHED FOR GENES RELATED TO MULTI-DRUG RESISTANCE AND CHEMOTAXIS

Pellegatta, S., Pessina, S., Cantini, G., Kapetis, D., Cazzato, E., Finocchiaro, G.

Journal:

Year:

2014

Language:

english

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148

REPEATED INTRANASAL APPLICATION OF NEURAL STEM CELL-MEDIATED ENZYM/PRODRUG THERAPY USING A NOVEL HSV-THYMIDINE KINASE VARIANT IMPROVES THERAPEUTIC EFFICIENCY IN AN INTRACRANIAL GLIOBLASTOMA MODEL

Schmidt, N. O., Duhrsen, L., Reitz, M., Henze, M., Sedlacik, J., Riecken, K., Fehse, B., Westphal, M.

Journal:

Year:

2014

Language:

english

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149

INTEGRATED ANALYSIS IDENTIFIES DIFFERENT METABOLIC SIGNATURES WITHIN BOTH TUMOR-INITIATING CELLS AND STEM CELLS IN A MURINE GLIOBLASTOMA MODEL

Sampetrean, O., Saya, H.

Journal:

Year:

2014

Language:

english

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150

MOLECULAR GENETIC DETERMINANTS OF LONG-TERM SURVIVAL WITH GLIOBLASTOMA

Weller, M., Weber, R. G., Riehmer, V., Kaulich, K., Willscher, E., Wirth, H., Gietzelt, J., Hentschel, B., Westphal, M., Simon, M., Schackert, G., Schramm, J., Matschke, J., Sabel, M. C., Gramatzki, D

Journal:

Year:

2014

Language:

english

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151

SOX2 IDENTIFIES THE TREATMENT-REFRACTORY STEM CELL POPULATION IN GROUP 2 MEDULLOBLASTOMA

Singh, S. K., Manoranjan, B., Venugopal, C., Vora, P., McFarlane, N., Garg, N., Singh, M., Mann, A., Bakhshinyan, D., Mahendran, S., Dunn, S.

Journal:

Year:

2014

Language:

english

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152

A PHASE I STUDY OF CONVECTION-ENHANCED DELIVERY OF LIPOSOMAL-IRINOTECAN USING REAL-TIME IMAGING WITH GADOLINIUM IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA

Butowski, N., Bankiewicz, K., Kells, A., Martin, A., Berger, M., Aghi, M., Prados, M., Chang, S., Clarke, J.

Journal:

Year:

2014

Language:

english

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153

EGFR PHOSPHORYLATION OF DCBLD2 RECRUITS TRAF6 AND STIMULATES AKT-PROMOTED TUMORIGENESIS

Cheng, S., Feng, H., Lopez, G. Y., Kim, C. K., Duncan, C. G., Alvarez, A., Nishikawa, R., Nagane, M., Su, A.-J., Auron, P. E., Hedberg, M. L., Wang, L., Grandis, J. R., McLendon, R. E., Bigner, D. D.,

Journal:

Year:

2014

Language:

english

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154

OPTIMIZATION OF DEMETHYLATING THERAPY FOR IDH1 MUTANT GLIOMAS

Riggins, G. J., Borodovsky, A.

Journal:

Year:

2014

Language:

english

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155

ASSESSING THE UTILITY OF CLINICAL TUMOR SEQUENCING IN THE PEDIATRIC NEURO-ONCOLOGY CLINIC

Parsons, D. W., Roy, A., Monzon, F. A., Lopez-Terrada, D. H., Chintagumpala, M. M., Berg, S. L., Hilsenbeck, S. G., Wang, T., Adesina, A. M., Li, X.-N., Kerstein, R. A., Scollon, S., Bergstrom, K., St

Journal:

Year:

2014

Language:

english

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156

RAPID IDH1 GENE MUTATION ANALYSIS FOR INTRAOPERATIVE PATHOLOGICAL DIAGNOSIS

Adachi, J.-i., Mishima, K., Suzuki, T., Fujimaki, T., Nishikawa, R.

Journal:

Year:

2014

Language:

english

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157

SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) ASSOCIATED WITH GLIOMA SURVIVAL

Wrensch, M., Walsh, K. M., Smirnov, I. V., Rice, T., Hansen, H. M., Molinaro, A. M., McCoy, L. S., Bracci, P. M., Cabriga, B. S., Perry, A., Marshall, R., Pekmezci, M., Zheng, S., Wiemels, J. L., Tiha

Journal:

Year:

2014

Language:

english

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158

PRELIMINARY RESULTS OF A PROSPECTIVE FEASIBILITY PILOT STUDY OF "GEMPOX" (GEMCITABINE, OXALIPLATIN, AND PACLITAXEL) IN PEDIATRIC AND ADULT PATIENTS WITH REFRACTORY OR RECURRENT CENTRAL NERVOUS SYSTEM (CNS) GERM CELL TUMORS (GCT): THE INTERNATIONAL CNS GCT CONSORTIUM TRIAL, CNS GCT-4

Finlay, J. L., Liu, Y., Haley, K., Erdreich-Epstein, A., Rushing, T., Grimm, J., Wong, K. E., Kiehna, E., Krieger, M. D., Gilles, F., Badie, B., D'Apuzzo, M., Dhall, G.

Journal:

Year:

2014

Language:

english

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159

CLINICAL TRIALS OF A THIRD-GENERATION RECOMBINANT ONCOLYTIC HSV-1 IN RECURRENT GLIOBLASTOMA AND OLFACTORY NEUROBLASTOMA PATIENTS

Todo, T., Tanaka, M., Ito, M., Ito, H., Ino, Y.

Journal:

Year:

2014

Language:

english

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160

INCREASED PERFUSION DUE TO VASCULAR NORMALIZATION IMPROVES OXYGENATION AND SURVIVAL IN GLIOBLASTOMA PATIENTS TREATED WITH CEDIRANIB WITH OR WITHOUT CHEMORADIATION

Batchelor, T. T., Gerstner, E. R., Emblem, K. E., Duda, D. G., Kalpathy-Cramer, J., Snuderl, M., Ancukiewicz, M., Polaskova, P., Pinho, M. C., Jennings, D., Plotkin, S. R., Chi, A. S., Eichler, A. F.,

Journal:

Year:

2014

Language:

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161

MUTANT IDH1-DRIVEN CELLULAR TRANSFORMATION INCREASES RAD51-MEDIATED HOMOLOGOUS RECOMBINATION AND TEMOZOLOMIDE (TMZ) RESISTANCE.

Pieper, R. O., Ohba, S., Mukherjee, J.

Journal:

Year:

2014

Language:

english

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162

PROGNOSTIC SIGNIFICANCE OF CLINICAL, HISTOPATHOLOGICAL, AND MOLECULAR CHARACTERISTICS OF MEDULLOBLASTOMAS IN THE PROSPECTIVE HIT2000 MULTICENTER CLINICAL TRIAL COHORT

Pietsch, T., Schmidt, R., Remke, M., Korshunov, A., Hovestadt, V., Jones, D. T., Felsberg, J., Kaulich, K., Goschzik, T., Kool, M., Northcott, P. A., von Hoff, K., von Bueren, A. O., Friedrich, C., Sk

Journal:

Year:

2014

Language:

english

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163

BRAIN TUMOR SURGERY NAVIGATION SYSTEM BASED ON UPDATING PREOPERATIVE IMAGES USING POSITIONAL INFORMATION OF SURGICAL TOOLS

Wakabayashi, T., Fujii, M., Natsume, A., Motomura, K., Hayashi, Y., Mori, K.

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Year:

2014

Language:

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164

Author-Index

Journal:

Year:

2014

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2014

165

NOVEL ALKYLPHOSPHOCHOLINE ANALOGS FOR BROAD SPECTRUM CANCER IMAGING AND THERAPY

Kuo, J. S., Weichert, J. P., Clark, P. A., Kandela, I. K., Vacaro, A., Clark, W., Longino, M., Pinchuk, A., Farhoud, M., Swanson, K. I., Floberg, J., Traynor, A., Hall, L. T., Pazoles, C.

Journal:

Year:

2014

Language:

english

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166

MECHANISMS OF ADAPTIVE RADIOPROTECTION IN GLIOMA STEM CELLS

Journal:

Year:

2014

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167

EPIGENETICALLY DISTURBED NEURAL STEM/PROGENITOR CELLS IN THE PRE-NEOPLASTIC STAGE OF PDGF-INDUCED MOUSE GLIOMA

Nister, M., He, X., Karimi, M., Hedren, A., Ekstrom, T. J.

Journal:

Year:

2014

Language:

english

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168

INHIBITING INVASION AND STEMNESS IN GLIOBLASTOMA BY THYMOSIN BETA 4 GENE SILENCING: A POTENTIAL THERAPEUTIC TARGET?

Tabatabai, G., Wirsching, H.-G., Krishnan, S., Florea, A.-M., Frei, K., Krayenbuhl, N., Hasenbach, K., Reifenberger, G., Weller, M.

Journal:

Year:

2014

Language:

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169

HISTOPATHOLOGIC EVALUATION OF H3K27ME3 IS A PROGNOSTIC BIOMARKER FOR PEDIATRIC GLIOBLASTOMAS

Judkins, A. R., Venneti, S., Santi, M., Felicella, M. M., Sullivan, L. M., Dolgalev, I., Martinez, D., Perry, A., Lewis, P. W., Allis, D. C., Thompson, C. B.

Journal:

Year:

2014

Language:

english

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170

INFORMING TREATMENT DECISIONS IN RELAPSED PEDIATRIC MALIGNANCIES USING NEXT-GENERATION DIAGNOSTICS

Pfister, S. M., Jones, D. T. W., Capper, D., Witt, R., van Tilburg, C., von Deimling, A., Eggert, A., Lichter, P., Witt, O.

Journal:

Year:

2014

Language:

english

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171

THE ROLE OF MYELOID DERIVED SUPPRESSOR CELLS (MDSCS) IN TUMOR-INDUCED IMMUNOSUPPRESSION IN HUMAN AND MURINE GLIOMAS

Vogelbaum, M. A., Otvos, B., Raychaudhuri, B., Hambardzumyan, D., Finke, J., Lathia, J.

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Year:

2014

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172

Course-Program

Journal:

Year:

2014

Language:

english

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173

FREQUENT H3F3A K27M MUTATIONS IN THALAMIC GLIOMAS FROM YOUNG ADULT PATIENTS

Mukasa, A., Aihara, K., Gotoh, K., Saito, K., Nagae, G., Tsuji, S., Tatuno, K., Yamamoto, S., Takayanagi, S., Narita, Y., Shibui, S., Aburatani, H., Saito, N.

Journal:

Year:

2014

Language:

english

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174

EXTRACELLULAR REGULATORS OF GLIOBLASTOMA SIGNALING

Phillips, J. J., Wade, A., Tran, V. M., McKinney, A.

Journal:

Year:

2014

Language:

english

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175

STEM- AND PROGENITOR-LIKE CELL CONTRIBUTION TO MALIGNANT ASTROCYTOMA HETEROGENEITY

Petritsch, C., Lerner, R., Lewis, K., Andor, N., Ozawa, T., Yoshida, Y., McMahon, M., Nicolaides, T., David James, C.

Journal:

Year:

2014

Language:

english

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176

HIGH INTERSTITIAL FLUID PRESSURE REGULATES TUMOR GROWTH AND DRUG UPTAKE IN HUMAN GLIOBLASTOMA

Persson, A. I., Ilkhanizadeh, S., Miroshnikova, Y. A., Frantz, A., Lakins, J. N., James, C. D., McKnight, T. R., Berger, M. S., Bergers, G., Weiss, W. A., Weaver, V. M.

Journal:

Year:

2014

Language:

english

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177

STRUCTURAL VARIANTS SHUFFLE CHROMATIN TO ACTIVATE GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA

Northcott, P. A., Lee, C., Zichner, T., Lichter, P., Korbel, J. O., Wechsler-Reya, R. J., Pfister, S. M.

Journal:

Year:

2014

Language:

english

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178

ROBUST INDUCTION OF TYPE-1 CD8+ T-CELL RESPONSES IN WHO GRADE II LOW-GRADE GLIOMA PATIENTS RECEIVING PEPTIDE-BASED VACCINES IN COMBINATION WITH POLY-ICLC

Okada, H., Butterfield, L. H., Hamilton, R. L., Hoji, A., Sakaki, M., Ahn, B. J., Kohanbash, G., Drappatz, J., Engh, J., Amankulor, N., Lively, M. O., Chan, M. D., Salazar, A. M., Potter, D. M., Shaw,

Journal:

Year:

2014

Language:

english

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179

EPIGENETIC TARGETING OF HEDGEHOG PATHWAY TRANSCRIPTIONAL OUTPUT

Cho, Y.-J., Tang, Y., Schubert, S., Willardson, M., Bandopadhayay, P., Bergthold, G., Nguyen, B., Masoud, S., Vue, N., Balansay, B., Gholamin, S., Cheshier, S. H., Atwood, S. X., Whitson, R. J., Lee,

Journal:

Year:

2014

Language:

english

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180

EVOLUTION OF THE GLIOBLASTOMA GENOME IN RESPONSE TO TREATMENTS

Nam, D.-H., Kim, J., Cho, H. J., Lee, I.-H., Kong, D.-S., Seol, H. J., Lee, J.-I., Park, W.-Y.

Journal:

Year:

2014

Language:

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181

GLIOMA SURGERY: TAILORING INTRAOPERATIVE NEUROPHYSIOLOGICAL STRATEGIES TO CLINICAL CONDITIONS ENHANCES RESECTION, EXTENDS INDICATIONS, AND KEEPS PATIENT FUNCTIONAL INTEGRITY

Bello, L., Comi, A., Riva, M., Pessina, F., Alfiero, T., Raneri, F., Fornia, L., Ferpozzi, V., Fava, E., Cerri, G.

Journal:

Year:

2014

Language:

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182

A 3-DIMENSIONAL MATRIX ASSAY THAT MAY HELP PREDICT TREATMENT RESPONSE TO TEMOZOLOMIDE IN PATIENTS WITH GLIOBASTOMA: SUBGROUP ANALYSIS OF PATIENTS UNDERGOING MGMT TESTING

Megyesi, J. F., Costello, P., McDonald, W., Macdonald, D., Easaw, J.

Journal:

Year:

2014

Language:

english

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183

BRAIN TUMOR CARE THROUGH THE PATIENT'S EYES -- THE VALUE OF A COMPREHENSIVE BRAIN TUMOR CENTER

Rosenblum, M. L., Robin, A., Walbert, T., Mikkelsen, T., Kalkanis, S., Rosenblum, M.

Journal:

Year:

2014

Language:

english

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184

MOLECULAR-BASED GRADING IN IDH-MUTANT LOWER GRADE GLIOMAS

Aldape, K., Zadeh, G., Sulman, E.

Journal:

Year:

2014

Language:

english

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185

DISTINCT COPY NUMBER ALTERATIONS AND INCIDENCE OF CHROMOTHRIPSIS ASSOCIATED WITH GRADE AND PROGNOSIS IN IDH MUTANT AND WILD-TYPE GLIOMAS

Colman, H., Cohen, A., Aldape, K., Sato, M., Mason, C., Diefes, K., Heathcock, L., Abegglen, L., Shrieve, D., Couldwell, W., Schiffman, J.

Journal:

Year:

2014

Language:

english

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186

CDKN2A LOSS IS ASSOCIATED WITH SHORTENED SURVIVAL IN INFILTRATING ASTROCYTOMAS BUT NOT OLIGODENDROGLIOMAS OR MIXED OLIGOASTROCYTOMAS

Perry, A., Reis, G. F., Pekmezci, M., Hansen, H. M., Marshall, R. E., Rice, T., Wiencke, J. F., Wrensch, M. R., Walsh, K. M., Perry, A.

Journal:

Year:

2014

Language:

english

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187

EX VIVO METABOLIC SIGNATURES OF GLIOMAS BASED UPON TUMOR GRADE, IMAGING CHARACTERISTICS AND TREATMENT HISTORY

Nelson, S. J., Elkhaled, A., Jalbert, L., Wen, Q., Phillips, J. J., Molinaro, A., Berger, M., Chang, S. M.

Journal:

Year:

2014

Language:

english

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188

PREOPERATIVE DYNAMIC CONTRAST-ENHANCED MRI CORRELATES WITH MOLECULAR MARKERS OF HYPOXIA AND VASCULARITY IN SPECIFIC AREAS OF INTRATUMORAL MICROENVIRONMENT AND IS PREDICTIVE OF PATIENT OUTCOME

Jensen, R., Salzman, K., Schabel, M.

Journal:

Year:

2014

Language:

english

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189

A NEW CLINICAL GUIDELINE (2007) AND NATIONAL AWARENESS CAMPAIGN (2011) ACCELERATED BRAIN TUMOUR DIAGNOSIS IN UK CHILDREN (HEADSMART - BE BRAIN TUMOUR AWARE)

Walker, D. A., Chu, T., Shah, A., WIlne, S., Coleman, M.

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2014

Language:

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english, 2014

190

CELL INTRINSIC SEXUAL DIMORPHISM IN THE RB AND P21 PATHWAYS UNDERLIES MALE PREDOMINANCE IN GBM

Rubin, J. B., Sun, T., Warrington, N. M., Luo, J., Brooks, M., Dahiya, S., Sengupta, R.

Journal:

Year:

2014

Language:

english

File:

PDF, 26 KB

english, 2014

191

ABERRANT SPLICING OF A BRAIN-ENRICHED ALTERNATIVE EXON ELIMINATES TUMOR SUPPRESSOR FUNCTION AND PROMOTES ONCOGENE FUNCTION DURING BRAIN TUMORIGENESIS

Bredel, M., Ferrarese, R., Harsh, G. R., Yadav, A. K., Bug, E., Maticzka, D., Reichardt, W., Masilamani, A. P., Dai, F., Kim, H., Hadler, M., Scholtens, D. M., Yu, I. L. Y., Beck, J., Srinivasasainage

Journal:

Year:

2014

Language:

english

File:

PDF, 27 KB

english, 2014

192

HUR DEPENDENT REGULATION OF CENTROSOMES

Nabors, L. B., Filippova, N., Yang, X.

Journal:

Year:

2014

Language:

english

File:

PDF, 24 KB

english, 2014

193

FINAL RESULTS OF A PROSPECTIVE MULTI-INSTITUTIONAL PHASE II STUDY OF EVEROLIMUS (RAD001), AN MTOR INHIBITOR, IN PEDIATRIC PATIENTS WITH RECURRENT OR PROGRESSIVE LOW-GRADE GLIOMA. A POETIC CONSORTIUM TRIAL

Kieran, M. W., Yao, X., Macy, M., Leary, S., Cohen, K., MacDonald, T., Allen, J., Boklan, J., Smith, A., Nazemi, K., Gore, L., Trippett, T., DiRenzo, J., Narendran, A., Perentesis, J., Prabhu, S., Pin

Journal:

Year:

2014

Language:

english

File:

PDF, 32 KB

english, 2014

194

KIAA1549:BRAF FUSION GENE IN PEDIATRIC BRAIN TUMORS OF DIFFERENT HISTOGENESIS

Giangaspero, F., Antonelli, M., Badiali, M., Buttarelli, F. R., Moi, L., Sanson, M.

Journal:

Year:

2014

Language:

english

File:

PDF, 26 KB

english, 2014

195

SPONTANEOUS IMMUNE RESPONSES IN GBM PATIENTS AFTER COMPLETE TUMOR RESECTION ARE ASSOCIATED WITH AN IMPROVED SURVIVAL

Herold-Mende, C., Mossemann, J., Jungk, C., Ahmadi, R., Capper, D., von Deimling, A., Unterberg, A., Beckhove, P.

Journal:

Year:

2014

Language:

english

File:

PDF, 28 KB

english, 2014

196

VSTAT120 REDUCES THE INNATE INFLAMMATORY RESPONSE TO INFECTION AND ENHANCES ONCOLYTIC VIRAL THERAPY FOR GLIOBLASTOMA

Kaur, B., Meisen, W. H., Hardcastle, J., Wojton, J., Wohleb, E., Alvarez-Breckenridge, C., Pow-anpongkul, P., Godbout, J., Kaur, B.

Journal:

Year:

2014

Language:

english

File:

PDF, 29 KB

english, 2014

197

LOSS OF SPARC IN P53-NULL ASTROCYTES PROMOTES MACROPHAGE ACTIVATION AND PHAGOCYTOSIS RESULTING IN DECREASED TUMOR SIZE AND TUMOR CELL SURVIVAL

Rempel, S. A., Thomas, S. L., Schultz, C. R., Mouzon, E., Golembieski, W. A., El Naila, R., Radakrishnan, A., Bobbitt, K. R., Lemke, N., Gutierrez, J. A., Poisson, L. M.

Journal:

Year:

2014

Language:

english

File:

PDF, 31 KB

english, 2014

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